Which is NOT an adverse reaction of corticosteroids?

Corticosteroids are a class of medications widely used for their anti-inflammatory and immunosuppressive properties. They are known to have a range of potential adverse effects due to their impact on various metabolic processes and immune function.

Weight gain is a common adverse reaction associated with corticosteroid use, primarily due to increased appetite and changes in fat distribution. Hyperglycemia is another notable effect because corticosteroids can impact glucose metabolism, making it essential to monitor blood sugar levels, especially in patients with diabetes.

Increased risk of infections occurs because corticosteroids can suppress the immune response. This immunosuppressive property diminishes the body's ability to fight off infections, leading to a higher susceptibility in individuals using these medications.

Respiratory distress, however, is not a typical adverse effect of corticosteroids. While corticosteroids can be administered to manage conditions that cause respiratory distress, such as asthma or COPD, they do not themselves cause respiratory distress as a side effect. In fact, when used appropriately, they can help alleviate inflammation in the airways and improve breathing.

Thus, the correct answer identifies respiratory distress as not being an adverse reaction of corticosteroids, in contrast to the other options which are well-documented effects of these medications.