What serious adverse reaction is associated with Penicillin use?

Anaphylaxis is a serious and potentially life-threatening allergic reaction that can occur in response to penicillin use. This reaction is characterized by rapid onset severe symptoms such as difficulty breathing, swelling of the face and throat, a rapid or weak pulse, and a drop in blood pressure, which can lead to shock. Anaphylaxis requires immediate medical intervention, typically with the administration of epinephrine and subsequent supportive care.

In clinical practice, it is crucial for healthcare providers to monitor patients who are prescribed penicillin for any signs of allergic reactions, especially in patients with a known history of penicillin allergy. While other reactions, such as rash, nausea, and fatigue, can also occur with penicillin, they are generally less severe and not classified as serious adverse reactions. The quick recognition and treatment of anaphylaxis are vital to ensure patient safety, making awareness of this potential reaction paramount when using penicillin antibiotics.