What is a common side effect associated with the use of statins?

Muscle pain or myopathy is a well-documented common side effect associated with the use of statins. Statins work by inhibiting an enzyme involved in the production of cholesterol in the liver, which can lead to various effects on muscle tissue. These muscle-related side effects can range from mild discomfort to severe conditions such as rhabdomyolysis, a serious breakdown of muscle tissue that can lead to kidney damage. The mechanism behind this includes potential disruption of mitochondrial function in muscle cells, which is thought to be involved in the development of myopathy.

While headaches, nausea, and dry mouth can also occur in patients taking various medications, they are not as closely associated with statin use as muscle pain is. Studies and clinical observations have consistently highlighted myopathy as a primary concern for patients on statin therapy, making it a crucial consideration for healthcare providers when prescribing these medications and monitoring patient tolerance.